MTech Principles Of Biochemical Engineering syllabus for 1 Sem 2020 scheme 20BBC13

Module-1 HISTORICAL DEVELOPMENT OF BIOPROCESS TECHNOLOGY 0 hours

HISTORICAL DEVELOPMENT OF BIOPROCESS TECHNOLOGY:

An overview of traditional and modern applications of biotechnological processes, Roles and responsibilities of a Chemical engineer in bioprocess industry, Steps in bioprocess development. Biology of the cell, classification, construction and cell nutrients. Industrial enzymes -, Nomenclature and Classification of enzymes, structure and functions of enzymes with relevant case studies.

Module-2 EQIPMENTS 0 hours

EQIPMENTS:

Mixing-Power requirement (Calculation of power no), Ungassed and gassed fluids, factors affecting the broth viscosity, Mixing equipments (Banbury mixers, Muller Mixers), Size Reduction(laws of size reduction, Mechanical efficiency and crushing efficiency Concept of Sphericity, Volume surface Mean Diameter, Arithmetic Mean Diameter, Mass mean diameter, Volume Mean Diameter and Proof for sphericity is unity for regular object) Crushing equipments (Jaw crusher, Garyatory crusher, Shredders, Ball mill) Filtration (constant pressure and constant rate filtration explanations with only the equations.

A d v e r t i s e m e n t
Module-3 INDUSTRIALLY IMPORTANT FILTRATION EQUIPMENTS AND ACCESSORIES 0 hours

INDUSTRIALLY IMPORTANT FILTRATION EQUIPMENTS AND ACCESSORIES:

(Rotary filters, Plate and frame filters and Leaf filters) Settling and its type (free and hindered settling: equation for Newton’s, Intermediate Stokes regimes and Criteria for selection of the equation) Problems, Size Enlargement operations. Flow pattern in agitated vessel, Role of shear in fermentation broth, bubble shear, rheological behavior of fermentation broth, 3-D Continuity equation, Pressure drop in flow through packed bed and Fluidized bed (Kozeny, Carman, Blake Plummer Equations), Flow of compressible fluids, Time to empty the liquid from a tank (Rectangle Tank and Hemispherical Tank), problems, Problems on calculation of resultant velocity and resultant acceleration of fluid on space ordinates (x, y, z). Numerical Problems.

Module-4 BASICS OF THERMODYNAMICS 0 hours

BASICS OF THERMODYNAMICS:

Procedure for Energy balance and Energy balance for cell culture, Concept of Internal energy, Enthalpy-calculations procedure (Enthalpy and internal energy changes calculations using first law of Thermodynamics), calculations of Entropy changes (Entropy changes for constant Temperature, Constant volume, constant pressure and work lost due to entropy) Differential equations of Entropy, Problems on entropy and Its calculations, Gibbs Free energy and other free energies of systems, Effect of temperature and Pressure on the Gibbs free energy and Helmholtz free energy. Discussion of case studies.

Module-5 INTRODUCTION TO HEAT TRANSFER 0 hours

INTRODUCTION TO HEAT TRANSFER:

Overview of Industrial Heat Exchangers (Construction and working principle of DPHE, STHE, Helical coil heat exchangers along with the heat transfer equations) and Concept of LMTD, Boiling Condensation, Nucleate and film boiling (Regimes of pool boiling) Regenerators and Recupretors. Transient growth kinetics, measurement of microbial population by turbidometry and studying the effect of temperature, pH, carbon and nitrogen Batch, fed batch and continuous cultures. Discussion of design strategies and case studies.

 

Course outcomes:

At the end of the course the student will be able to:

  • Demonstrate strong basics in principles of bioengineering.
  • Tackle live problems in various spheres of biochemical engineering.
  • Search for information from relevant data hand books, for the design and execution of experiments using bioreactors / fermenters

 

Question paper pattern:

The SEE question paper will be set for 100 marks and the marks scored will be proportionately reduced to 60.

  • The question paper will have ten full questions carrying equal marks.
  • Each full question is for 20 marks.
  • There will be two full questions (with a maximum of four sub questions) from each module.
  • Each full question will have sub question covering all the topics under a module.
  • The students will have to answer five full questions, selecting one full question from each

 

Textbook/ Textbooks

1 Bioprocess Engineering and principles2nd Edition Paulin and M Doran Wiley 2006

2 R.M. Felder and R.W. Rousseau Elementary Principles of Chemical Processes, 3rd Edition J. Wiley 2000

 

Reference Books

1 SC Arrora and Domkundar Process Heat Transfer 3 rd edition Wiley 2006

2 K.V. Narayan Engineering Thermodynamics 3 rd edition 2010 3 R.K. Bansal Fluid Mechanics 3rd edition 2010

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