STRUCTURE OF BIO-MATERIALS AND BIO-COMPATIBILITY
Definition and classification of bio-materials, mechanical properties, composite materials, Nanomaterials and nanocomposites, Tissue-biomaterial interactions, biomaterial characterization, medical devices, Testing of biomaterials: In-vitro, invivo pre-clinical tests, safety and biocompatibility evaluation
METALS AND CERAMICS
Metallic implant materials, stainless steels, Co-based alloys, Ti-based alloys, ceramic implant materials, aluminum oxides, hydro-apatite, glass ceramics, carbons.
SYNTHETIC AND BIOPOLYMERS
Polymerization, poly amides, Acrylic polymers, rubbers, high strength thermoplastics, Bio polymers: Collagen, Hyaluronic acid, chitosan and Elastin.
ARTIFICIAL ORGANS
Artificial Heart, Prosthetic Cardiac Valves, Limb prosthesis, Externally powered limb prosthesis, Dental Implants, Artificial cornea, Artificial liver and pancreas, artificial skin.
APPLICATIONS
Medical applications of biomaterials, Drug delivery, Bioinspired Materials and Biomimetics, Tissue engineering, Regenerative medicine, Stem cell biology, modern scaffold structures, advanced fabrication technologies including computer-aided tissue engineering and organ printing, global regulatory requirements, technology transfer and ethical issues
Course outcomes:
At the end of the course the student will be able to:
• Students should be able to0 understand the principles and features of polymeric materials,identifyand understand key structure-property-processing relationship of polymers
• Students should understand the roles of polymer design play in the biomedical applications.
Question paper pattern:
The SEE question paper will be set for 100 marks and the marks scored will be proportionately reduced to 60.
• The question paper will have ten full questions carrying equal marks.
• Each full question is for 20 marks.
• There will be two full questions (with a maximum of four sub questions) from each module.
• Each full question will have sub question covering all the topics under a module.
• The students will have to answer five full questions, selecting one full question from each module.
Textbooks
1 Fundamentals of Biomaterials VasifHasirci, NesrinHasirci Springer 2018
2 Biomaterials, Medical Devices, and Combination Products - Biocompatibility Testing and Safety Assessment Shayne Cox Gad, Samantha GadMcDonald CRC Press 2015
Reference Books
1 Joon B. Park, Roderic S. Lakes Biomaterials – An Introduction Springer 2010
2 Hench L. Larry and Jones J. Biomaterials, Artificial organs and Tissue Engineering Woodhead Publishing Limited, 2005
3 Marek J. Los, AndrzejHudecki, Emilia Wiechec Marek J. Los, AndrzejHudecki, Emilia Wiechec Associated Press 2018