MTech Advancedbioinformatics Lab syllabus for 1 Sem 2018 scheme 18BBIL16

Module-1 LABORATORY EXPERIMENTS 48 hours

LABORATORY EXPERIMENTS

1. Sequence retrieval from nucleic acid and protein databases.

2. Retrieval of information about structure, bioassay chemical compounds (such as Drugs and naturally occurring compounds).

3. Retrieval of information about physical and Chemical properties of chemical compounds (such as Drugs and naturally occurring compounds).

4. Gene sequence assembly and contig mapping and identification of Gene.

5. Primer and Promoter design for a given sequences

6. Sequence searches using FASTA and BLAST, and Phylogenetic analysis.

7. Prediction of secondary structure for given protein and RNA sequences.

8. Retrieval of protein structure from PDB and its visualization and modification.

9. Prediction of 3D structure of unknown protein sequence.

10. Prediction of protein-protein interactions.

11. EST clustering and EST mapping, and Genome annotation

12. Microarray data analysis- normalization, clustering.

13. Study of Profiles, Patterns and PSSMs

 

Course outcomes:

• Students would learn to appreciate the various algorithms used for diverse exercises. Students would gain knowledge about various softwares and their multitude of applications.