Fundamentals of Biotechnology
Basic terms in biotechnology, recombinant DNA technology, genetic engineering, gene cloning. Development of nanobiotechnology, timelines and progress. Basics of cell orgenells. Biomacromolecules- carbohydrates, lipids, proteins and nucleic acids, PHA, cyanophcin inclusion, magnetosome, alginates, bacteriophages, S-layer protein, bacteriorhodpsin. Biological building blocks; Sizes of building blocks and comparison with nanostructures.
Nanostructures:
DNA and protein based nanostructures, DNA origami, DNA nanotubes, polypeptide nanowire and protein nanoparticles, SAM, biological nanomotor. Nanoconjugates: DNA-gold nanoconjugates. DNA based nanoelectronics: immobilization of DNA on substrates, probing the electronic properties of single DNA molecules. Manipulation of DNA on metal surfaces.
Interaction between biomolecules and nanoparticle surface
Different types of inorganic materials used for the synthesis of hybrid nano-bio assemblies, Application of nano in biology, nanoprobes for Analytical Applications - A new methodology in medical diagnostics and Biotechnology, Current status of Nanobiotechnology, Future perspectives of Nanobiology.
Applications of nanomaterials
Drug delivery and gene delivery, Nanobiochips, biosensors. Nanomaterials in bone substitutes and dentistry. Polymeric nanofibres-tissue engineering, smart capsules, microemulsions, nano based cancer therapy, nanorobotics. Lotus leaf as a model self-cleansing system. Diatoms as example for silicon biomineralization. Biomechanical strength properties of Spider silk.
Photoinduced Electron Transport in DNA
Electronic Devices Based on DNA Architecture, DNA Nanowires, Charge Transport, DNA-Based Nanoelectronics, Electrical Manipulation of DNA on Metal Surfaces, Nanostructured Bio-compartments, DNA-Gold nanoconjugates.