17BT44 Bioprocess Principles & Calculations syllabus for BT



A d v e r t i s e m e n t

Module-1 BASIC CHEMICAL CALCULATIONS AND MATERIAL BALANCE 10 hours

BASIC CHEMICAL CALCULATIONS AND MATERIAL BALANCE:

Concept of atom and mole, expressing composition of mixtures in Solids, liquids and gases. Expressing composition of mixtures and solutions - Percentage by weight percentage, mole percentage and Volume percentage; Normality, Morality, Molality. Generalized material balance equations for distillation, absorption, extraction, crystallization, mixing, drying & evaporation.

Module-2 MATERIAL BALANCE WITHOUT CHEMICAL REACTIONS AND FUELS 10 hours

MATERIAL BALANCE WITHOUT CHEMICAL REACTIONS AND FUELS

Material balances calculation in Distillation, Absorption, Extraction, Crystallization, Drying, Mixing and Evaporation Operations, Fuels – types of fuels, (solid, liquid and gaseous fuel), relevance to biofuels, characteristics of fuels, Ultimate and proximate analyses of fuels..

Module-3 MATERIAL BALANCE INVOLVING CHEMICAL REACTIONS 10 hours

MATERIAL BALANCE INVOLVING CHEMICAL REACTIONS:

Material balances calculation involving bypass, recycle and operations. Generalized material balance equations, Principles of stoichiometry, Definitions of limiting and excess reactants, fractions and percentage conversion, yield and percentage yield, Selectivity, unit process – neutralization, oxidation, nitration, hydrolysis, and problems relating to these unit processes.

Module-4 ENERGY BALANCE 10 hours

ENERGY BALANCE:

General energy balance equation for steady state. Heat capacity, estimation of heat capacity for solids, liquids, gases and their mixtures. Enthalpy, Standard Heat of formation, standard heat of reaction, Standard heat of combustion and calorific value, Calculation of heat of reaction at elevated temperature.

Module-5 BIOPROCESS PRINCIPLES & STOICHIOMETRY OF BIOPROCESS 10 hours

BIOPROCESS PRINCIPLES & STOICHIOMETRY OF BIOPROCESS:

Historical development of bioprocess technology; Bioprocess principles and operations, generalized process flow sheets. General material balance equation for steady state (for manufacture of penicillin and ethanol) - outline of a bioprocess and the various (upstream and downstream) unit operations involved in bioprocesses. Stoichiometry of microbial growth and product formation.

 

Course outcomes:

After studying this course, students will be able to:

  • Discuss the significance of material and energy balance for bioprocess technology.
  • Solve problems related to material and energy balance to give solutions for bioprocess development.
  • Develop the flow-sheet for general processes operating in bioprocess industry.
  • Appreciate the stoichiometry of microbial growth and product formation involved in bioprocess technology

 

REFERENCE BOOKS

1. Basic Principles and Calculations in Chemical Engineering by David Himmelblau, PHI

2. Bioprocess Engineering by Shule and Kargi, Prentice Hall.

3. Chemical Process Calculations by R. Asokan, University Press, 2011.

 

TEXT BOOKS

1. Principles of Biochemistry by David L. Nelson (Editors), W.H. freeman and company.

2. Bioprocess Engineering Principles by Pauline Doran, Academic Press.

3. Biochemical Engg. Fundamentals by J E Bailey & D. F. Ollis, McGraw Hill.

4. Biochemical Calculations by I.H.Segel, John Wiley & Sons

Last Updated: Tuesday, January 24, 2023